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Switching to olive oil could reduce risk of cardiovascular disease

Posted: 11 January 2022 | | No comments yet

A new study has suggested that replacing margarine and other fats with olive oil could reduce the risk of cardiovascular disease, though other scientists say more research is needed to prove this.

Olive oil poured on spoon

Consuming more than seven grams (>0.5 tablespoon) of olive oil per day is associated with lower risk of cardiovascular disease mortality, cancer mortality, neurodegenerative disease mortality and respiratory disease mortality, according to a study published in the Journal of the American College of Cardiology. The study found that replacing about 10 grams/day of margarine, butter, mayonnaise and dairy fat with the equivalent amount of olive oil is associated with lower risk of mortality as well.

“Our findings support current dietary recommendations to increase the intake of olive oil and other unsaturated vegetable oils,” said Marta Guasch-Ferré, PhD, a senior research scientist at the Department of Nutrition at Harvard T.H. Chan School of Public Health and the study’s lead author.

“Clinicians should be counselling patients to replace certain fats, such as margarine and butter, with olive oil to improve their health. Our study helps make more specific recommendations that will be easier for patients to understand and hopefully implement into their diets.”

Using participants from the Nurses’ Health Study and the Health Professionals Follow-up Study, researchers analysed 60,582 women and 31,801 men who were free of cardiovascular disease and cancer at the study baseline in 1990. During 28 years of follow-up, diet was assessed by a questionnaire every four years. The questionnaire asked how often, on average, they consumed specific foods, types of fats and oils, as well as which brand or type of oils they used for cooking and added at the table in the previous year.

Olive oil consumption was calculated from the sum of three items in the questionnaire: olive oil used for salad dressings, olive oil added to food or bread, and olive oil used for baking and frying at home. One tablespoon was equivalent to 13.5 grams of olive oil. The consumption of other vegetable oils was calculated based on the participants reported oil brand and type of fat used for cooking at home. Margarine and butter consumption was based on the reported frequency of stick, tub or soft margarine consumption, and the amount of margarine or butter added from baking and frying at home. Intakes of dairy and other fats and nutrients were also calculated.

The researchers found olive oil consumption increased from 1.6 grams/day in 1990 to about four grams/day in 2010, while margarine consumption decreased from about 12 grams/day in 1990 to about four grams/day in 2010. The intake of other fats remained stable.

Olive oil consumption was categorized as follows:

  • Never or <1 time per month
  • >0 to ≤4.5 grams/day (>0 to ≤1 teaspoon)
  • >4.5 to ≤7 grams/day (>1 teaspoon to ≤1/2 tablespoon)
  • >7 grams/day (>1/2 tablespoon)

When researchers compared those who rarely or never consumed olive oil, those in the highest consumption category had 19 percent lower risk of cardiovascular mortality, 17 percent lower risk of cancer mortality, 29 percent lower risk of neurodegenerative mortality and 18 percent lower risk of respiratory mortality. The study also found substituting 10 grams/day of other fats, such as margarine, butter, mayonnaise and dairy fat, with olive oil was associated with 8-34% percent lower risk of total and cause-specific mortality. They found no significant associations when substituting olive oil for other vegetable oils.

“It’s possible that higher olive oil consumption is a marker of an overall healthier diet and higher socioeconomic status. However, even after adjusting for these and other social economic status factors, our results remained largely the same,” Guasch-Ferré said. “Our study cohort was predominantly a non-Hispanic white population of health professionals, which should minimize potentially confounding socioeconomic factors, but may limit generalisability as this population may be more likely to lead a healthy lifestyle.”

In an accompanying editorial, Susanna C. Larsson, PhD, associate professor of epidemiology at the Karolinska Institutet in Stockholm, said: “The current study and previous studies have found that consumption of olive oil may have health benefits. However, several questions remain. Are the associations causal or spurious? Is olive oil consumption protective for certain cardiovascular diseases, such as stroke and atrial fibrillation, only or also for other major diseases and causes of death? What is the amount of olive oil required for a protective effect? More research is needed to address these questions.”

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