Whitepaper: The determination of non-intentionally added substances (NIAS) as a part of ‘safety-by-design’
With no legally prescriptive guidelines on how to assess the safety of NIAS, what approach should be taken?
Ever-advancing analytical instrumentation provides very powerful tools for determination of IAS and NIAS. As instruments become more readily available and sensitivity increases there is the potential for more and more NIAS to be detected. However, identification and quantification are still providing challenges.
Framework regulation state that FCM manufacturers are obliged to ensure the safety of their products and that safety of NIAS must be assessed. However, presently there are no levels of migration or exposure set for which compliance with this requirement can be demonstrated.
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