article

QA/QC In-Depth Focus 2018

Posted: 25 April 2018 | | No comments yet

In this In-Depth Focus, Tania Portolés looks at how experts can expand the detection and quantification of contaminants in food samples and David Stadler and Rudolf Krska discuss the impact of lot-to-lot variation’s use on determining the accuracy of a multi-mycotoxin assay.

QA/QC In-Depth Focus 2018
  • Expanding the detection and quantification of contaminants in food samples
    Monitoring contaminants in seafood samples is crucial, but developments in regulations and marine feed mean the situation is constantly changing. Tania Portolés explains her work at the Research Institute for Pesticides and Water (IUPA), Spain, in ensuring food security in such samples.
  • Lot-to-lot variation: A neglected issue in method validation of LC-MS-based assays
    Food analysis, particularly the determination of contaminants and residues, is often based on LC-MS methods in combination with external solvent-based or matrix-matched calibration. The performance of such methods is typically evaluated by in-house validation from replicate analysis of a single lot of a matrix. However, different lots of a matrix might have different extraction recovery factors (RE) or signal suppression/enhancement (SSE) effects, resulting in lot-to-lot variation. Therefore, failing to consider this variation might lead to an underestimation of the uncertainty of the measurement result. Here, David Stadler and Rudolf Krska from the University of Natural Resources and Life Sciences, Vienna, discuss the impact of the lot-to-lot variation on the accuracy of a multi-mycotoxin assay.

 

This In-Depth Focus is restricted - login or subscribe free to access

New Food cover 2 2018Thank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.

Why subscribe? Join our growing community of thousands of industry professionals and gain access to:

  • bi-monthly issues in print and/or digital format
  • case studies, whitepapers, webinars and industry-leading content
  • breaking news and features
  • our extensive online archive of thousands of articles and years of past issues
  • ...And it's all free!

Click here to Subscribe today Login here

 

Send this to a friend