A robust and sensitive method for the direct analysis of polar pesticides in food and environmental samples without derivatisation
This application note discusses how some polar compounds are not amenable to the extraction procedure. It discusses how chromatographic methods or poor ionisers require additional single-residue methods which involve time-consuming preparation and separation, and often involve derivatisation to improve detection.
The challenge of polar pesticides
The prevalence of multi-residue LC-MS/MS analyses for the quantification of pesticides in food and environmental samples has been steadily increasing for many years, and they are now considered to be a minimum requirement of most laboratories working in these fields. Modern tandem quadrupoles are capable of detecting such regulated compounds at very low levels with minimal sample preparation, such as QuEChERS, thereby enabling labs to process large numbers of samples for many analytes with a fast turnaround.
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