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Application Note: Max performance in GC/MS/MS analysis of 200 pesticides in challenging food matrices

Learn best practices to enhance analytical performance for the analysis of > 200 pesticides in challenging matrices using Agilent triple quadrupole GC/MS instruments.

This application note describes five best practices to enhance analytical performance in the analysis of over 200 pesticides in challenging matrices including spinach, walnut, and cayenne pepper. The novel Agilent Captiva EMR passthrough cleanup procedure following the Agilent QuEChERS extraction enabled a cleaner matrix background. The cleanup and extraction reduced matrix interferences with target analytes and extended the maintenance-free operation time of the instrument. Calibration performance was demonstrated over a wide dynamic range to over four orders of magnitude. It was shown that the Agilent 8890/7000E triple quadrupole GC/MS system achieved excellent linearity over a concentration range of 0.1 to 5,000 ppb. The Agilent 8890/7010C triple quadrupole GC/MS system demonstrated superior sensitivity yielding a higher signal-to-noise ratio at lower concentrations.