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Quantitation of cannabinoids in hemp flower by derivatisation GC/MS

In this application, offline derivatisation of hemp sample extract was performed to determine THC and quantitate commonly analysed cannabinoids

Total potency and total THC are two important calculations in the distinction of cannabis and hemp. Following U.S. Federal laws, hemp must be less than 0.3% total THC (by dry weight). In this application, offline derivatisation of hemp sample extract was performed to determine total THC and quantitate an additional nine commonly analysed cannabinoids by GC/MS. The derivatisation allows for direct analysis and measurement of the thermally labile acids that are naturally occurring in hemp, which simplifies the determination of total THC