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Application note: Low calibration limit research for multiresidue pesticides in milk using the Agilent 8890/7010B and 7890B/7000C triple quadrupole GC/MS systems

This application describes the Agilent 7890B/7000C and 8890/7010B triple quadrupole GC/MS systems for pesticide analysis in milk and linearity ranges

To ensure the safety of milk and dairy products, some countries have issued a series of regulations limiting pesticide residues. To meet these limits, reference methods have been defined in the regulations. The maximum allowed pesticide residues in milk are mostly much lower than those for fruits and vegetables in government regulations.1 These lower levels require an advanced analytical platform to achieve the required high sensitivity. This application note describes two GC/MS/MS platforms: the Agilent 7890B/7000C and the Agilent 8890/7010B triple quadrupole GC/MS systems. Both are applicable for pesticide analysis in milk and their corresponding linearity ranges, respectively. The results demonstrate that the 8890/7010B system provides 1 ng/mL detection of almost 60% of pesticides, while 10% could be detected at 1 ng/mL on the 7890B/7000C system.