Rainer Schuhmacher - Articles and news items
Issue 5 2013 • 4 November 2013 • Rudolf Krska and Rainer Schuhmacher, Center for Analytical Chemistry, Department for Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences Vienna (BOKU)
As a result of the global marketplace, the safety of food and feed has become of increasing concern for consumers, governments and producers. Several highly publicised worldwide incidents related to chemical contaminants such as mycotoxins in food and feed have also attracted much media attention. Mycotoxins are toxic natural secondary metabolites produced by fungi on agricultural commodities in the field and during storage under a wide range of climatic conditions. Mycotoxins are potent toxins and have a wide range of actions on animals and humans, e.g. cyto-, nephro- and neurotoxic, carcinogenic, mutagenic, immunosuppressive and estrogenic effects. Most of the occurrence studies have emphasised ‘traditional’ mycotoxins, such as aflatoxins, ochratoxin A, zearalenone, fumonisins and trichothecenes.
Issue 1 2009 • 20 February 2009 • Michael Sulyok, Rainer Schuhmacher & Rudolf Krska, Centre for Analytical Chemistry, Department for Agrobiotechnology, IFA Tulln, University of Natural Resources and Applied Life Sciences Vienna
Since the introduction of atmospheric pressure ionisation liquid chromatography-mass spectrometry (API-LC-MS) in the early 1990s, there was a continuous effort to further improve the performance of the LC-MS instruments concerning sensitivity and robustness. One result of this development is the trend towards methods that are designed to simultaneously analyse a large number of analytes with little or even without any sample clean-up and/or analyte enrichment. It is evident that this approach exhausts the capabilities of the mass spectrometers to the extreme. In this article, the difficulties that are usually encountered during the development of such a multi-analyte method are discussed using the example of mycotoxins.
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