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PAT - Articles and news items

Infrared spectroscopy and its role to monitor wine fermentation

Issue 4 2013  •  28 August 2013  •  Daniel Cozzolino School of Agriculture, Food and Wine, University of Adelaide

The term Process Analytical Technologies (PAT) describes the field of process analysis and measurement technologies that have been expanded to include several physical, chemical, mathematical and other analytical tools used to characterise chemical and biological processes. Over the past few years, on- in- and at-line analysis, the so-called PAT technologies, have demonstrated themselves to be one of the most efficient and advanced tools for continuous monitoring, as well as controlling the processes and the quality of raw ingredients and products in several applications among food processing, petrochemical and pharmaceutical industries.

PAT in large-scale dairy processing

Issue 2 2013  •  26 April 2013  •  Tristan Hunter, Technical Manager – Strategy, Fonterra Co-operative Group Ltd

Open any magazine aimed at the pharmaceutical manufacturing industry and there are regular references to Process Analytical Technology (PAT). There has been a significant focus on this area ever since publication of the US Food and Drug Administration (FDA) report in 20041 encouraging the pharmaceutical industry to adopt PAT. Touted benefits include process optimisation, improved product consistency, reduced downgrade and even real-time release of product to market.

In a nutshell: Mario Becker, Sartorius Group

Issue 4 2011  •  6 September 2011  •  Mario Becker, VP Marketing and Product Management, PAT & Automation, Sartorius Group

Founded in 1870, the Sartorius Group is an international leading laboratory and process technology provider focused on the biopharma, pharma and food and beverage industries. In their strategy to help customers efficiently implement complex lab and production processes, Process Analytical Technology (PAT) is an essential contribution to process and quality optimisation. PAT has historically been rooted in the pharmaceutical industry with the FDA guidance document released in 2004 as a framework for innovative pharmaceutical development, manufacturing and quality assurance. “PAT is a risk-based approach for designing, analysing and controlling manufacturing processes, which is moving step-by-step toward the food industry. In this context we see a clear trend to shift the analytics of the lab in the process,” Becker explains. “PAT combines process analytics with software systems to measure and control Critical Process Parameters (CPPs) influencing the Critical Quality Attributes (CQAs) of intermediates and finished products. In the food industry, process analysers are mainly used for process optimisation and real-time process control.”

 

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